People

Professor John Mattick

John Mattick

Group leader

John Mattick is SHARP Professor of RNA Biology at UNSW Sydney. He was recently previously Executive of Genomics England (2018-2019), and Director of the Garvan Institute of Medical Research in Sydney (2012-2018), where he established one of the first HiSeq X10 sequencing and clinically accredited genome analysis facilities. He was previously the Foundation Director of the Institute for Molecular Bioscience and the Australian Genome Research Facility at the University of Queensland. He has published over 300 research articles and reviews, which have been cited over 94,000 times, and is the #1 ranked scholar globally in noncoding RNA and #4 ranked scholar in RNA

He is a Fellow of the Australian Academy of Science, the Australian Academy of Health & Medical Sciences, and the Australian Academy of Technology & Engineering. He is also an Associate Member of the European Molecular Biology Organization. He has received numerous awards including the inaugural Gutenberg Chair at the University of Strasbourg, the International Union of Biochemistry and Molecular Biology Medal, the Human Genome Organisation Chen Medal for Distinguished Academic Achievement in Human Genetics and Genomic Research, and the University of Texas MD Anderson Cancer Center Bertner Award for Distinguished Contributions to Cancer Research.

 j.mattick@unsw.edu.au

Dr. Mitchell Cummins

Mitchell Cummins

Senior Postdoctoral Fellow

I am a postdoctoral research fellow in the Mattick lab. My research focuses on investigating the function of ultra-conserved elements in animal genomes, especially in placental mammals. I also investigate the characteristics and roles of lncRNAs, with a particular interest in central nervous system (CNS) lncRNAs. I completed my PhD(Anatomy) at the University of Newcastle under supervisor Associate Professor Doug Smith investigating age-related changes in the CNS.

 mitchell.cummins@unsw.edu.au

Saba Altaf

Saba Altaf

Postdoctoral Fellow

Hi! I am Saba — an RNA biologist and molecular neuroscientist with a passion for understanding how the brain works at the molecular level.
I completed my PhD here in the Mattick Lab at UNSW Sydney in 2026, where I investigated the subcellular localisation of brain lncRNAs, their protein interactions, and their roles in spatial learning and memory. Before coming to UNSW, I completed my Master of Philosophy in Molecular Biology at the University of the Punjab, Pakistan, where I researched the genetics of asthma susceptibility.
I am now working as a Postdoctoral Research Associate, working on an ARC Discovery Project exploring how long non-coding RNAs regulate cognition and brain function — using spatial transcriptomics, proteomics, and in vivo approaches in rodent models. Outside the lab, I am passionate about science communication and mentoring the next generation of researchers.

 s.altaf@unsw.edu.au

Tansel Ersavas

Tansel Ersavas

PhD student 2021-present

Hello, I’m Tansel. I have extensive experience in developing complex systems, with a special interest in Artificial Intelligence, mobile computing, and XR/VR technologies. Before pursuing my PhD, I worked as an Associate Director at KPMG, where I specialized in AI-based solutions, and I led the "Deep Learning Initiative" at the Garvan Institute of Medical Research for four years.
My expertise spans deep learning, reinforcement learning, generative AI, large language models (LLMs), intelligent agents, robotics, animatronics, and immersive applications using VR and XR. I’ve applied these technologies in diverse industries, including healthcare/biotechnology and finance/banking.
Recently, my research has focused on the application of deep learning to nanopore RNA sequencing and leveraging Convolutional Neural Networks for analyzing high-dimensional non-image datasets in genomics, transcriptomics, and proteomics.

 t.ersavas@unsw.edu.au

Rowan Heggen

PhD student 2026-present

 r.heggen@unsw.edu.au

Positions available

Please email if you are interested in a PhD or postdoc position in the lab.

Our Collaborators

Dr. Scott Berry

Single Molecule Science, UNSW

details

Dr. Martin Smith

Ramaciotti Centre for Genomics

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Associate Professor Kelly Clemens

School of Psychology, UNSW

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Professor Lars Ittner

Dementia Research Centre, Macquarie University

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Dr. Daniel Fernandez Ruiz

School of Biomedical Sciences, UNSW

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Research

Our lab focuses on exploring the diverse roles of long non-coding RNAs (lncRNAs) in cellular and developmental biology. We aim to uncover their contributions to various biological processes.

Key areas of our research include:

Structure-Function Relationships

Investigating how the structural properties of lncRNAs relate to their biological functions and molecular interactions.

Subnuclear Organization

Characterizing subnuclear organelles enriched with specific lncRNAs and uncovering their roles in cellular function.

Brain Function and Cognition

Exploring brain-expressed lncRNAs and their involvement in cognition, memory, and motor functions.

Genomic Associations

Studying lncRNAs expressed from genomic regions associated with complex traits and disorders to reveal their regulatory mechanisms.

Immune Regulation

Identifying lncRNAs that control immune cell differentiation and their contributions to immune system dynamics.

Evolutionary Conservation

Exploring the evolution and functional significance of ultraconserved elements in vertebrates.

Our research integrates advanced genomics, molecular biology, and computational approaches, with the ultimate goal of unraveling the intricate biology of lncRNAs and their contributions to health and disease.